Exercise as a method to reduce the risk of oral cancer: A narrative review

Background: Cancer is a major cause of death worldwide. One the most common forms cancer oral cancer, which can occur due to exposure carcinogenic factors, such as tobacco cigarettes, alcohol, betel-nut chewing, ultraviolet rays or human papillomavirus infection. Physical exercise known have many benefits and contribute reducing risk minimising side-effects treatment increasing curative effect treatment. Purpose: This study aimed explain role method reduce risk. Reviews: Studies examining impact on are currently limited lack research this subject. However, according several laboratory experimental studies Mus musculus test subjects, moderate-intensity contributes suppressing proliferation development squamous epithelial cells, subsequently become cells. Exercise also increase intracellular proteins that induce apoptosis in cells (e.g. wild protein p53, ratio Bax/Bcl-2, caspase-3), decrease p53 mutant expression transformed trigger cancer. must be optimally performed prevent control symptoms, although exact duration intensity required humans not been established. Conclusion: plays by inducing preventing lead developing